pentobarbital will enhance the degree or outcome of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of ivosidenib with potent CYP3A4 inducers decreased ivosidenib plasma concentrations.pentobarbital will raise the stage or impact of clopidogrel by affecting hepatic/intestin